Left ventricular dilatation and diastolic compliance changes during chronic volume overloading.

نویسندگان

  • W H McCullagh
  • J W Covell
  • J Ross
چکیده

The magnitude and time course of alterations in left ventricular size, end-diastolic pressure (LVEDP), and stiffness consequent to chronic volume overloading were examined in conscious dogs. A large infrarenal aortocaval shunt was produced surgically, left ventricular dimensions were measured by cineradiography using radiopaque beads implanted subendocardially, and LVEDP was measured via an indwelling catheter. In nine experimental and seven control animals, LVEDP was related to the left ventricular end-diastolic diameter (LVEDD) over a range of LVEDP produced by transfusion and bleeding. In control studies LVEDP averaged 6.7 1.42 (SEM)

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عنوان ژورنال:
  • Circulation

دوره 45 5  شماره 

صفحات  -

تاریخ انتشار 1972